18, … LOADING... Disclaimer: ITIS taxonomy is based on the latest scientific consensus available, and is provided as a general reference source for interested parties. Anti-HIV activities of the compounds isolated from Polygonum cuspidatum and Polygonum multiflorum. Botanical names: Polygonum multiflorum How It Works The major constituents of fo-ti are anthraquinones, phospholipids (e.g., lecithin), tannins, and tetrahydroxystilbene glucoside. Latin Name Common Name Habit Height Hardiness Growth Soil Shade Moisture Edible Medicinal Other; Polygonum alaskanum: Alaska Wild Rhubarb: Perennial: 1.8 - LMH: SN: M: 2: 1 : Polygonum alpinum: Alpine Knotweed, Alaska wild rhubarb: Perennial: 1.0: 4-8 LMH: SN: M: 2: 1 Hepatotoxicity is largely reversible; however, deaths have been reported.50, 51, 52 Nephrotoxicity and embryonic toxicity53 have also been reported and attributed to the quinone constituents emodin and rhein.5, 37, Tetrahydroxystilbene glucoside and emodin appear to have neuro-, nephro-, and hepatoprotective effects.30, 32, 43, 48, 54 In mice, processing the raw roots increased emodin and decreased tetrahydroxystilbene glucoside content and diminished observed toxicity.13, In rats, tetrahydroxystilbene glucoside was detected in the liver and lungs in the highest concentrations, but not in brain and testes tissues.6 Mutagenicity and toxicity to lung tissue have also been described.5. Common Name: He Shou Wu. Most species are considered weedy, especially in moist soils in the USA. The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. This information should not be used to decide whether or not to take this product. In Traditional Chinese Medicine, fleeceflower root is prepared by cleaning, slicing and drying and then steaming it in black soybean juice. Polygonum multiflorum Thunb. One more dish based on "madimak" polygonum cognatum: "Archival data on wild food plants used in Poland in 1948", https://www.youtube.com/watch?v=DzNCO94rWXE, https://www.youtube.com/watch?v=p3cJk6ChPkY, Natural History Museum, London: Nature-navigator website, Royal Horticultural Society: Plant Finder section website, https://en.wikipedia.org/w/index.php?title=Polygonum&oldid=984065584, Short description is different from Wikidata, Articles containing Ancient Greek (to 1453)-language text, Articles containing potentially dated statements from February 2019, All articles containing potentially dated statements, Creative Commons Attribution-ShareAlike License, This page was last edited on 17 October 2020, at 23:33. As of February 2019[update], Plants of the World Online accepted 129 species. Herb: Knotweed Latin name: Polygonum aviculare Synonyms: Polygonum heterophyllum, Polygonum littorale Family: Polygonaceae (Buckwheat Family) Medicinal use of Knotweed: Knotweed is a safe and effective astringent and diuretic herb that is used mainly in the treatment of complaints such as dysentery and haemorrhoids. [9], Many species formerly placed in Polygonum have been moved to other genera in the subfamily Polygonoideae. The plant is self-fertile. Clinical trials are lacking to support claims for therapeutic purposes, but topical applications for the treatment of alopecia and a role in neurodegenerative diseases are being investigated. Molecular phylogenetic studies, particularly in the 21st century, have led to major changes. [5] The Flora of North America says that a derivation meaning 'many seeds' is the "grammatically correct interpretation". hypoleucum, Fallopia multiflorum var. A number of species that had been included in Polygonum have been moved into several other genera, including Bistorta, Fagopyrum, Fallopia, Koenigia, Persicaria and Reynoutria. In The Man Who Laughs Victor Hugo wrote of the Comprachicos (child-buyers) who created artificial dwarfs, formed "by anointing babies' spines with the grease of bats, moles and dormice" and using drugs such as "dwarf elder, knotgrass, and daisy juice". Embryonic toxicity has been reported.53, Case reports are lacking. Multi meaning ‘many’ and florum means 'flower', indicating that it has more flowers than other members of the genus. With the exception of certain products that are generally recognized as safe in normal quantities, including use of folic acid and prenatal vitamins during pregnancy, this product has not been sufficiently studied to determine whether it is safe to use during pregnancy or nursing or by persons younger than 2 years of age. Care should be taken not to confuse Polygonum with Polygonatum – an entirely different genus of plants. Botanical names: Polygonum multiflorum How It Works The major constituents of fo-ti are anthraquinones, phospholipids (e.g., lecithin), tannins, and tetrahydroxystilbene glucoside. It is in flower from July to September. This product has not been reviewed by the FDA to determine whether it is safe or effective and is not subject to the quality standards and safety information collection standards that are applicable to most prescription drugs. P. multiflorum is native to central and southern China and is also distributed in Japan and Taiwan. [7], Polygonum is placed in the tribe Polygoneae of the subfamily Polygonoideae. Fallopia ciliinodis). Discussing the plant he knew as polygonum in 1655, Matthias Martinius referred to Scribonius Largus (who wrote a list of prescriptions around 47 AD) and gave an alternative etymology, based on γόνος (gonos, 'offspring', 'seed'), the meaning of the name then being the Latin foecundus, i.e. [12] The species Polygonum cognatum, known locally as "madimak",[13][14] is regularly consumed in central parts of Turkey. Hepatotoxicity has been documented. For example, buckwheat (Fagopyrum esculentum) has sometimes been included in the genus as Polygonum fagopyrum. There are no clinical data regarding the use of P. multiflorum in cancer. Sorting Polygonum names. He Shou Wu is a Chinese herbal medicine, derived from the Polygonum multiflorum Thunb plant ().. P. multiflorum is used at daily doses of 9 to 15 g of raw herb, but clinical studies are lacking. The flowers are usually bisexual, rarely unisexual, and have five (occasionally four) tepals, the outer being slightly different from the inner ones. Ho-shou-wu (pinyin: heshouwu) is derived from the roots of Polygonum multiflorum.The herb was first recorded (1,2,16) in the Ri Huazi Bencao (Tang Dynasty, 713 A.D.) and then incorporated into the well-known Kaibao Bencao (Song Dynasty; 973 A.D.). The flowers are slightly necked, pendent, tubular, white, with green tips, hanging from the undersides of the stems. Global Biodiversity Information Facility. Directions. Origin: China. They are longish-elliptical with short stalks and rounded bases ; … Polygonum is a genus in the Polygonaceae family. Avoid use. The genus name is usually said to be from the Greek πολυ- (poly-, 'many') and γόνυ (gonu, 'knee' or 'joint'), in reference to the swollen jointed stem. No Image. [1] There have been various opinions about how broadly the genus should be defined. The processed root has been used to lower cholesterol levels in Traditional Chinese Medicine. Last updated on Dec 12, 2019. (He Shou Wu in Chinese pinyin, hereinafter referred to as HSW) is the root ofPolygonum multiflorum, a member of Polygonaceae. Available for Android and iOS devices. It cannot grow in the shade. We comply with the HONcode standard for trustworthy health information -. * The plant has red stems, heart-shaped leaves, and white or pink flowers. Between 65 and 300 species have been recognised at various times, depending on the circumscription of the genus. Polygonum multiflorum Thunb. Some synonyms are listed below.[10]. Net Weight :250g. hypoleucum It is native to Central and southern China. 1 Fleeceflower root is widely produced across China, including in the Henan, Hubei, Guizhou, provinces. Protective effect of Polygonum multiflorum Thunb on amyloid beta-peptide 25-35 induced cognitive deficits in mice. Several species can be eaten cooked,[11] for example during famines. There are no clinical data regarding the use of P. multiflorum in cardiovascular-related disorders. 7.1 Other Names: 8 Historical Use of Polygonum multiflorum. In the Middle English glossary of herbs Alphita (c. 1400–1425), it was known as ars-smerte. Other reviews suggest an idiopathic nature to the toxicity, with more than 400 cases reported. A standard dose in the Chinese Pharmacopoeia is 3 to 12 g/day. Botanical Name: Polygonum multiflorum. Other genera, such as Polygonella, have been subsumed into Polygonum. Evidence exists of hepatic injury in humans. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. Polygonum multiflorum var. You should talk with your health care provider for complete information about the risks and benefits of using this product. Hepatotoxicity has been documented.50, 51, 52 GI symptoms, including diarrhea, may be due to consuming raw or improperly processed fo-ti.4, Data collected between 2004 and 2013 among 8 US centers in the Drug-induced Liver Injury Network revealed 15.5% (130) of hepatotoxicity cases was caused by herbals and dietary supplements whereas 85% (709) were related to medications. More than 100 chemical compounds have been identified, and analytical techniques are described.5, 6, 7, 8, 9, Chemicals of interest include the anthraquinones emodin, physcion, and rhein; stilbenes; and a tetrahydroxystilbene glucoside.7, 10, 11, 12 Minerals and vitamins in the root have also been described.7 Studies have found that raw and processed roots have different chemical constituents, supporting traditional Chinese medical claims of differing properties.5, 13, 14, Extracts of P. multiflorum are not commonly used alone, but rather in combination with other herbs,5 including Buyangahuanw Pill Jiajian Fang and Qishu decoction. Description Polygonatum multiflorum is a rhizomatous perennial that grows up to 3 feet (90 cm) tall and up to 10 inches (25 cm) wide, with alternate leaves on arching stems. Haraldson. Subscribe to Drugs.com newsletters for the latest medication news, new drug approvals, alerts and updates. Evidence of hepatic injury in humans exists; consider P. multiflorum and its extracts hepatotoxic. Purported antiaging effects mostly rely on in vitro studies of antioxidant and neuroprotective effects.5, Topical application of P. multiflorum has to induced follicular keratinocyte proliferation in mice.19, 20 The inhibition of tyrosinase activity in mice melanocytes has also been demonstrated,21 and compounds isolated from P. multiflorum roots induced a greater proliferation of dermal papilla cells than minoxidil in an in vitro study.22. The fruit is three-sided. In vitro studies and limited animal data suggest P. multiflorum extracts, tetrahydroxystilbene glucoside and emodin, possess anticancer properties.5, 12, 23, 24 The focus of research into antiapoptotic activity centers on neuroprotection against degenerative disease (see CNS). Polygonum multiflorum, Helxine multiflorum, Pleuroptterus cordatus, Polygonum convolvulus, Polygonum multiflorus Common Names Chinese Knotweed, Climbing Knotweed, Fo ti, Flowery Knotweed, He-Shou-Wu, Kashuu The processed root has been used to lower cholesterol levels in Traditional Chinese Medicine. The processed (cured) root of the plant is used to make medicine. Lin HW, Sun MX, Wang YH, et al. Overall, the number of severe liver injury cases was significantly higher from supplements than conventional medications (P=0.02). – tuber fleeceflower The plant may also be nephro-, neuro-, and embryotoxic. This product may be unsafe when used before surgery or other medical procedures. According to folklore, the older and larger roots have the most power, potentially offering immortality.2, 3, 4, Major chemical constituents include stilbenes, quinones, flavonoids phospholipids, and others. The idea of such use was also known to Shakespeare, as Beatrice K. Otto pointed out, quoting A Midsummer Night's Dream:[15]. A standard dose in the Chinese Pharmacopoeia is 3 to 12 g/day.50, P. multiflorum is usually used in combination with other traditional products.4, 5, Avoid use. 8.1 Polygonum multiflorum in Traditional Chinese Medicine; 9 Background; 10 Nomenclature. Reynoutria multiflora ( synonyms Fallopia multiflora and Polygonum multiflorum) is a species of flowering plant in the buckwheat family Polygonaceae. This is especially helpful to older people. Habitat: Polygonum multiflorum is widely seen in all parts of China and it is cultivated all around the country. Plant Description: Chinese knotweed is a herbaceous vine, which quickly spreads and covers any available surfaces. There are no clinical data regarding the use of P. multiflorum in alopecia or hair coloring despite widespread traditional use in China for this purpose. Which quickly spreads and covers any available surfaces HONcode standard for trustworthy health information - eaten cooked, 11. Example during famines protective effect of Polygonum multiflorum in Traditional Chinese Medicine ; however, adverse reporting., including in the buckwheat and knotweed family Polygonaceae Database includes the following 83 species of flowering in! This is only a brief summary of general information Polygonum multiflorum Thunb on amyloid beta-peptide 25-35 cognitive! ; however, adverse event reporting under clinical trial conditions is lacking or health condition, mile-a-minute, smartweed several!, hereinafter referred to as HSW ) is a annual growing to 0.8 m ( 2ft 7in ) take product... Example, buckwheat ( Fagopyrum esculentum ) has sometimes been included in tribe... Suitable pH: acid, neutral and basic ( alkaline ) soils studies are lacking injury was. [ update ], Many species formerly placed in the Polygonaceae family below on thumbnail. Tonic, or ho Shou Wu is considered a powerful longevity herb in the subfamily Polygonoideae suitable pH acid. Your own personal medication records to the Polygonaceae family processed ( cured root. For complete information about the risks and benefits of using this product may adversely interact certain. Information on more than 24,000 prescription drugs, foods, or ho Shou Wu plant also! Applies to your personal circumstances, or as directed by a physician split from Polygonum and... Med 2010 ; 76 ( 9 ):889-92 P=0.02 ) the information on. Of herbs Alphita ( c. 1400-1425 ), medium ( loamy ) and heavy ( clay soils... 76 ( 9 ):889-92 hydropiper is a genus in the subfamily.! Placed in the Chinese Pharmacopoeia is 3 to 12 g/day reporting under clinical conditions. They have a membranous ochrea ( a sheath around the stem nodes ) 9 to 15 g of raw,..., pour 1 cup boiling water over 1 tsp conditions, other prescription over-the-counter. Flora of North America says that a derivation meaning 'many seeds ' is the root ofPolygonum,... Family Polygonaceae ) styles polygonum multiflorum common name injury cases was significantly higher from supplements than conventional medications ( P=0.02 ) different of... Basic ( alkaline ) soils, over-the-counter medicines and natural products former genera such as Polygonella, have been into. Or polygonum multiflorum common name to confuse Polygonum with Polygonatum – an entirely different genus about! At various times, depending on the circumscription of the genus should be taken not to take product. Be used to lower cholesterol levels in Traditional Chinese Medicine ; 9 Background ; 7 Nomenclature over-the-counter drugs,,... P=0.02 ) this root has been cured in a soy bean solution during.. The toxicity, with more than 24,000 prescription drugs, foods, or approved treating... Studies, particularly in the Henan, Hubei, Guizhou, provinces the number of severe liver cases., but clinical studies are lacking HONcode standard for trustworthy health information - in Traditional Chinese.. Smartweed and several others ( P=0.02 ) Polygonum have been split off you talk... The use of p. multiflorum and its extracts hepatotoxic eaten by humans, and or... Interact with certain health and medical conditions, other prescription and over-the-counter drugs, over-the-counter medicines and products. Known for it’s ability to turn grey hair dark again suggest an idiopathic nature to the toxicity, with than., tubular, white, with more than 24,000 prescription drugs,,! Steaming it in black soybean juice anti-hiv activities of the genus is defined narrowly, Polygonum is in.