Matches between donors and recipients of different ethnicities are very common. The donor is a different human than the recipient and cannot be genetically identical (such as identical twins). Lymphocytotoxic cross-matching, which measures how the recipient’s antibodies react to the donor’s antigens. For example, a child would need a smaller organ than an adult. The body sizes of the donor and recipient. However, the immune system poses a significant barrier to successful organ transplantation when tissues/organs are transferred from one individual to another. Its policies and computerized network match donated organs with transplant candidates in ways that save as many lives as possible and provide transplant recipients with the best possible chance of long-term survival.. By far, kidneys are the most needed organs. When deciding who will receive kidney donations, the Organ Procurement and Transplantation Network considers the following: Blood type matches. A graft is the transplantation of an organ or tissue to a different location, with the goal of replacing a missing or damaged organ or tissue. Grafts are typically moved without their attachments to the circulatory system and must reestablish these, in addition to the other connections and interactions with their new surrounding tissues. The donor and recipient must have compatible blood types, for example. It saves thousands of lives each year. The current organ matching process is different for each organ type. Shared ethnicity is NOT a requirement for matching organ donors and recipients. To help prevent this reaction, doctors type, or match both the organ donor and the person who is receiving the organ. United Network for Organ Sharing provides a vital link in the organ transplant process. The organ is offered first to the transplant center with the candidate who is the best match. Patients on the waiting list are matched, in order of need, with organs that match their blood and tissue type, as well as size needed. Allograft: This type of transplant is a human to human transplant of tissues, organs, or corneas. Still, a more diverse donor registry gives ethnic minorities on the transplant waiting list a better chance to find a good donor match. Organ transplantation is a complex process that requires a close match between the recipient and donor. To develop a framework that works for each organ, each organ type will be looked at individually, starting with lung. There is a notable risk of rejection with this type of organ transplant. Using the same framework for all organs will improve organ allocation by creating consistency and transparency for the entire transplant community. Transplantation is the process of moving cells, tissues or organs from one site to another for the purpose of replacing or repairing damaged or diseased organs and tissues. 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