Subscribe to MedHelp's free newsletter for Community Support, Experience, and Guidance. I am off this med. Eating standing up as well as trying to watch a movie standing up as I could not sit for any length of time without the pain. Ideally, the majority of bacteria live in the large intestine, but with SIBO some colonies are displaced in the small intestine or the stomach where they don’t belong. Thank you for the update. Take it 30 minutes to 1 hour before your first meal of the day. I am sensitive to these medications. However, levothyroxine is not suitable for some people. I wonder if they way they say not to eat is really the best advice. Secondly, I had/have hypothyroidism. It feels raw! You can cut or crush the tablet. I just seem to be sensitive to medications (I also had severe stomach issues on generic hydroxychloroquine for my lupus and now only take name brand). Levothyroxine is a T4-only thyroid replacement medication (it must be converted after absorption to T3 (the active form usable by the cells). Stomach cramps, like the worst menstrual pain ever, gastro issues, dizziness, sweating, palpitations. I took dose first thing in the morning on empty stomach with glass water. I have had to switch to the generic as well. I can't figure out what to do or if I should see my doctor. Many people lose weight from high doses simply because they cannot hold down food. My doctor says, it'll subside over time or I can just cut back on it. I also like to use a hot water bottle on an area that hurts if needed. Data sources include IBM Watson Micromedex (updated 2 Feb 2021), Cerner Multum™ (updated 3 Feb 2021), ASHP (updated 29 Jan 2021) and others. Applies to levothyroxine: oral capsule liquid filled, oral tabletOther dosage forms: 1. injection powder for solutionAlong with its needed effects, levothyroxine may cause some unwanted effects. I can live with the all the gastro problems but not the painful twinges. Related Posts. I ve had the gastro problems but 2 days ago painful twinges began happening periodically in my upper right stomach (or maybe gallbladder). Now after two weeks after I take dose I immediately get stomach cramps.. not dibilitating but not fun... a little nauseous and goosebumps all over my arms with chills.Has anyone had any luck with this getting better or changing meds? Take levothyroxine in the morning. These are the is… A common cause for stomach noises and pain is poor digestion. Add proper vegan diet can provide plenty of protien. Stomach cramps, like the worst menstrual pain ever, gastro issues, dizziness, sweating, palpitations. They both have peroxidase enzymes. In general, though, I have no such side effect as this is a natural hormone replacement for the thyroid. Excessive nausea and diarrhea with some... How long do the side effects of Ozempic last? Am curious because you won't be the only one who has an effect. too. Can/does the drug Levothyroxine cause nausea & or vomiting? Pain so intense, pacing the floor at night as I could not sleep. I have the same. I just started levothyroxine. I didn't even want to lift my leg up to walk without extreme pain. I had touchy stomach before but levo has increased sensitivity. Entresto - Anyone have severe stomach cramps and pain? I started this medicine about a week ago. Ended up in n ER. It lowers stomach acid and also reduces absorption of thyroid drugs. Hi I am just wondering the same exact thing! I started Levothyroxine for the first time ever in Nov 2018. I have since stopped taking this medication and after about a week, my pain started to subside. I only take Cytomel, the levothyroxine, topamax for migraines and I have Relpax PRN for migraines. We do know that an overgrowth of bacteria can interfere with levothyroxine absorption. 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